• A white resealable pouch containing Reed Biotech reagents, with a printed insert showing a small vial and product information. The pouch has a clear top and bottom, and the front features the Reed Biotech logo and website text.
1 1

Reed Biotech

SWAP70 Mouse Monoclonal Antibody - RA12043

SWAP70 Mouse Monoclonal Antibody - RA12043

$360.00 CAD
$360.00 CAD
Sale Sold out
Size

Get a quote

SWAP70 Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA12043-50, RA12043-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: domain:The PH domain is essential for phosphatidylinositol 3, 4, 5-trisphosphate binding., function:Phosphatidylinositol 3, 4, 5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3, 4)-bisphosphate production and cell protrusion., PTM:Tyrosine-phosphorylated., similarity:Contains 1 PH domain., subcellular location:In resting B-cells it is localized mainly in the cytoplasm and upon cell activation it is recruited to the plasma membrane and then translocates to the nucleus. In activated, class-switching B-cells it is associated with membrane IgG but not IgM. Localized to loose actin filament arrays located behind actively extending lamellipodia., subunit:The SWAP complex consists of NPM1, NCL, PARP1 and SWAP70., tissue specificity:Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760).,

Reactivity: Human, Mouse, Rat, Monkey

Host: Mouse

Applications: WB, IP

Alternate Names: KIAA0640, 70kDa, AV235546, FLJ39540, HSPC321, SWA 70 protein, SWAP 70, SWAP switching B-cell complex 70kDa subunit, SWAP-70, SWAP70, Switch associated protein 70, Switch-associated protein 70, SWP70_HUMAN.

Clonality: Monoclonal

Dilution: wb 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 23075

Protein Molecular Weight（KDa): 70

Molecular Weight: 70

Research Use Only

View full details