SYCM Rabbit Polyclonal Antibody - BT-AP12921

SYCM Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12921-20, BT-AP12921-50, BT-AP12921-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome.

Research Areas: Epigenetics and nuclear signaling

Target Protein: CARS2

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SYCM

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9HA77; Mouse: Q8BYM8

Synonyms: SYCM; Probable cysteine--tRNA ligase; mitochondrial; EC 6.1.1.16; Cysteinyl-tRNA synthetase; CysRS

GeneID: Human: 79587; Mouse: 71941

Research Use Only