Syk (phospho Tyr348) rabbit pAb - ES1480

Syk (phospho Tyr348) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1480-50, ES1480-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],

Alternate Name: SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human SYK around the phosphorylation site of Tyr348. AA range:314-363

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 72kD

Human Gene ID: 6850

Human SWISS Prot NO: P43405

Subcellular Location: Cell membrane. Cytoplasm, cytosol.

Research Use Only