Product Description

SYNE3 Polyclonal Antibody

Catalogue Numbers: BS62409-50, BS62409-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q6ZMZ3

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB IF

All Applications: WB:1:500~1:1000 IF:1:50~1:200

Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SYNE3 polyclonal antibody detects endogenous levels of SYNE3 protein.

Extra Notes: Western blot (WB) analysis of SYNE3 polyclonal antibody at 1:500 dilution
LaneA:Aml-12 whole cell lysate
LaneB:H9C2 whole cell lysate
LaneC:A549 whole cell lysate
LaneD:HepG2 whole cell lysate
LaneE:HEK293T whole cell lysate

Bioworld Molecular Weight: ~ 112 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: C14orf139; C14orf49; KASH3; LINC00341; NCRNA00341; NET53; Nesp3; Nesprin3; Nesprin 3; Nesprin-3

Immunogen: Synthetic peptide, corresponding to Human SYNE3.

Conjugate: Unconjugated

Modification: Unmodified