SYNJ2 rabbit pAb - ES12859

SYNJ2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12859-50, ES12859-100

Citations, Manuals and MSDS Available upon request.

Background: The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human SYNJ2 AA range: 145-195

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 8871

Human SWISS Prot NO: O15056

Subcellular Location: Cytoplasm. Cell membrane. Membrane raft. Cell junction, synapse, presynapse. Cytoplasm, cytoskeleton. Localizes at presynapse terminals in brain and at bundles of microtubules surrounding the nucleus in the elongating spermatids corresponding to the manchette (By similarity). Translocates from the cytoplasm to membrane ruffles in a RAC1-dependent manner (PubMed:11084340).

Research Use Only