Synuclein-α Monoclonal Antibody - RA12048

Synuclein-α Monoclonal Antibody Size: 50μL, 100μL Catalogue Numbers: RA12048-50, RA12048-100 Citations, Manuals and MSDS Available upon request. Background: synuclein alpha (SNCA) Homo sapiens Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016], Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Storage Instructions: -20°C/1 year Applications: WB; IHC-p; IF (paraffin section) ; ELISA Species Cross-Reactivity: Human GeneID (Human): 6622 SWISS: P37840 Source: Mouse Research Use Only