Product Description

SYT (A7) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2069-50, BS2069-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1–5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x, 18) translocation resμlts in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2, both fusions resμlt in the production of transcriptional activators.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Protein SSXT, Protein SYT, Synovial sarcoma translocated to X chromosome protein, SS18, SSXT, SYT

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to the N-terminal of Human SYT.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SYT (A7) polyclonal antibody detects endogenous levels of SYT protein.

Molecular Weight: ~ 45 kDa

Pathway: ATP-Dependent Chromatin Remodeling Complexes,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15532

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only