SYT8 Polyclonal Antibody
Catalogue Numbers: BS60822-50, BS60822-100
Sizes: 50µl, 100µl
Alternative Name: Synaptotagmin-8; Synaptotagmin VIII; Syt VIII; SYT8
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8NBV8
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
IHC: 1:50~1:204
Background: Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. The Synaptotagmin family of proteins share a common domain structure that consists of a transmembrane domain and a cytoplasmic region composed of two C2 domains. Synaptotagmin VIII, also known as SYT8, is a 401 amino acid single-pass type III membrane protein belonging to the Synaptotagmin family. Containing two C2 domains, Synaptotagmin VIII exists as a homodimer or homooligomer. Synaptotagmin VIII exists as two alternatively spliced isoforms, isoform 1 and isoform 4. Synaptotagmin VIII isoform 4 is thought to participate in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -24°C long term. Avoid freeze-thaw cycles.
Specificity: SYT8 polyclonal antibody detects endogenous levels of SYT8 protein.
Bioworld Molecular Weight: ~ 18 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of SYT8 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human SYT8.
Conjugate: Unconjugated
Modification: Unmodified