Product Description

TAB3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA35198-50, RA35198-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3) Homo sapiens The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 78

Protein Molecular Weight (kDa): 78

Storage: -20°C/1 year

Human Gene ID: 257397

Human SwissProt Number: Q8N5C8

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only