TAF13 Polyclonal Antibody
Catalogue Numbers: BS61048-50, BS61048-100
Sizes: 50µl, 100µl
Alternative Name: Transcription initiation factor TFIID subunit 13; Transcription initiation factor TFIID 18 kDa subunit; TAF(II)18; TAFII-18; TAFII18; TAF13; TAF2K; TAFII18
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q15543
Host: Rabbit
Reactivity: Human, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: TFIID is a general transcription factor that facilitates the preinitiation complex assembly through direct interactions with the TATA promoter element. TFIID is a multisubunit complex consisting of a small TATA-binding polypeptide and other TBP-associated factors (TAFs). The TAF II family members include p18, p28, p32, p100, p130, p170 and p250, which is the largest subunit of TFIID. TAF II p32 is the human homologue of the Drosophila TAFII40 and is upregulated during apoptosis. TAFII p32 interacts with the activation domain of the viral protein 16, TFIIB and the class II transactivator (CIITA) to modulate transcription. The human and murine TAFII p32 proteins are distinct isoforms, designated TAF II p32 a and b, respectively, and are thought to have individual roles in regulation. TAF II p28 and TAF II p18 interact with one another in vitro and intracellularly, and both interact with TBP through distinct domains. TAF II p28 potentiates transactivation of the estrogen and vitamin D3 receptors (ER and VDR), and is the limiting factor in the RXRa activation pathway.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: TAF13 polyclonal antibody detects endogenous levels of TAF13 protein.
Bioworld Molecular Weight: ~ 14 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of TAF13 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lys Lane 2: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human TAF13.
Conjugate: Unconjugated
Modification: Unmodified