Product Description

TAF1C Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11664-50, MB11664-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q15572

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TAF1C in K562Lysates using TAF1C antibody.

Bioworld Molecular Weight: Calculated MW: 95 kDa; Observed MW: 95 kDa

Specificity: IgG

Alternative Name: SL1; TAFI95; TAFI110; MGC:39976

Immunogen: A synthetic peptide of human TAF1C

Conjugate: Unconjugated

Modification: Unmodified