Product Description

TAK1 (3G1) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3053-50, MB3053-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O43318

Host: Mouse

Reactivity: Human, Mouse, Rat,Monkey

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TAK1 in K562, Hela, MCF-7, COS7, 3T3 and C6Lysates using TAK1 antibody.

Bioworld Molecular Weight: Calculated MW: 67 kDa; Observed MW: 67,78 kDa

Specificity: IgG2b

Alternative Name: MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Immunogen: Purified recombinant human TAK1 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified