TAK1 (phospho-Ser412) Rabbit Polyclonal Antibody - RA30279

TAK1 (phospho-Ser412) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30279-50, RA30279-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase kinase kinase 7 (MAP3K7) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 6885

Protein MW (KDa): 70

SWISS: O43318

Source: Rabbit

Research Use Only