Product Description

TAK1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16400-50, BZ16400-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O43318

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: ICC/IF, WB, IHC-F, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 67 kDa; Observed MW: 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TAK1 in Jurkat lysates, treated with heat shock lysates using TAK1 antibody. The Lane on the right is blocked with the synthesized peptide., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using TAK1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of TAK1 in rat kidney using Tak1 antibody, and DAPI., Immunofluorescence analysis of TAK1 in mouse kidney using Tak1 antibody, and DAPI.

Alternative Name: MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human MAP3K7. AA range:161-210

Conjugate: Unconjugated

Modification: Unmodified