Product Description

Talin-1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21365-50, RA21365-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: talin 1 (TLN1) Homo sapiens This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF/ICC, ELISA

Alternate Names: TLN1, KIAA1027, TLN, Talin-1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Molecular Weight: 269

Protein Molecular Weight (kDa): 269

Storage: -20°C/1 year

Human Gene ID: 7094

Human SwissProt Number: Q9Y490

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only