Product Description

TANK Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30288-50, RA30288-100

Citations, Manuals and MSDS Available upon request.

Background: TRAF family member associated NFKB activator (TANK) Homo sapiens The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: TANK; ITRAF; TRAF2; TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein; I-TRAF

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 10010

Protein MW (KDa): 48

SWISS: Q92844

Source: Rabbit

Research Use Only