Product Description

Tartrate Resistant Acid Phosphatase Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65953-50, BS65953-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Tartrate-resistant acid phosphatase is an iron containing glycoprotein that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. TRAP is the most basic of the acid phosphatases and is the only form not inhibited by L+-tartrate. TRAP is a relatively minor lysosomal enzyme which may be activated in certain pathologies such as Hodgkin’s disease and B- and T-cell leukemias. Receptor activator of NFκB ligand (RANKL) plays an essential role in osteoclast differentiation and activation by increasing the expression of protease osteoclast markers such as TRAP. TRAP has collagenolytic activity and plays a major role in ligament degradation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: Type 5 acid phosphatase, Acid phosphatase 5 tartrate resistant, ACP5, PPA5_HUMAN, T5ap, Tartrate resistant acid ATPase, Tartrate resistant acid phosphatase type 5, Tartrate resistant acid phosphatase type 5 precursor, Tartrate-resistant acid ATPase, Tartrate-resistant acid phosphatase type 5, TR AP, TR-AP, TrATPase, Type 5 acid phosphatase.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human TRAP/Tartrate Resistant Acid Phosphatase:101-200/325

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: Tartrate Resistant Acid Phosphatase Polyclonal Antibody detects endogenous levels of Tartrate Resistant Acid Phosphatase protein.

Molecular Weight: 35 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P13686

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only