Tartrate Resistant Acid Phosphatase Polyclonal Antibody-BS65953

Tartrate Resistant Acid Phosphatase Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65953-50, BS65953-100

Swiss-Prot: P13686

Host: Rabbit

Tartrate Resistant Acid Phosphatase Polyclonal Antibody-BS65953

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,

Applications: WB,

All Applications: WB=1:500-2000

Background: Tartrate-resistant acid phosphatase is an iron containing glycoprotein that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. TRAP is the most basic of the acid phosphatases and is the only form not inhibited by L+-tartrate. TRAP is a relatively minor lysosomal enzyme which may be activated in certain pathologies such as Hodgkin’s disease and B- and T-cell leukemias. Receptor activator of NFκB ligand (RANKL) plays an essential role in osteoclast differentiation and activation by increasing the expression of protease osteoclast markers such as TRAP. TRAP has collagenolytic activity and plays a major role in ligament degradation.

Purification and Purity: affinity purified by Protein A

Specificity: Tartrate Resistant Acid Phosphatase Polyclonal Antibody detects endogenous levels of Tartrate Resistant Acid Phosphatase protein.

Bioworld Molecular Weight: 35 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-Tartrate Resistant Acid Phosphatase at 1/1000 dilution
, Primary: Anti-Tartrate Resistant Acid Phosphatase at 1/300 dilution

Alternative Name: Type 5 acid phosphatase; Acid phosphatase 5 tartrate resistant; ACP5; PPA5_HUMAN; T5ap; Tartrate resistant acid ATPase; Tartrate resistant acid phosphatase type 5; Tartrate resistant acid phosphatase type 5 precursor; Tartrate-resistant acid ATPase; Tartrate-resistant acid phosphatase type 5; TR AP; TR-AP; TrATPase; Type 5 acid phosphatase.

Immunogen: KLH conjugated synthetic peptide derived from human TRAP/Tartrate Resistant Acid Phosphatase:101-200/325

Modification: Unmodified

Conjugate: Unconjugated