Product Description

Tau (Phospho-Thr534/217) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65274-50, BS65274-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: microtubμle associated protein tau(MAPT) Homo sapiens This gene encodes the microtubμle-associated protein tau (MAPT) whose transcript undergoes complex, regμlated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jμl 2008],

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF(paraffin, section), ELISA

Alternate Names: MAPT, MAPTL, MTBT1, TAU, Microtubμle-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Thr534/217. AA range:181-230

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: Phospho-Tau (T534) Polyclonal Antibody detects endogenous levels of Tau protein only when phosphorylated at T534.

Molecular Weight: ~50-85kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P10636

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only