Product Description

Tau(Phospho-Thr534/217)Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65274-50, BS65274-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: P10636

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IHC-p,IF(paraffin section),ELISA

All Applications: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Background: microtubule associated protein tau(MAPT) Homo sapiens This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Phospho-Tau (T534) Polyclonal Antibody detects endogenous levels of Tau protein only when phosphorylated at T534.

Bioworld Molecular Weight: ~50-85kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of lysates from rat brain, using Tau (Phospho-Thr534/217) Antibody. The lane on the right is blocked with the phospho peptide.

Alternative Name: MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

Immunogen: The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Thr534/217. AA range:181-230

Conjugate: Unconjugated

Modification: Phosphorylation