TBL1 Mouse Monoclonal Antibody - RA12059

TBL1 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA12059-50, RA12059-100

Citations, Manuals and MSDS Available upon request.

Background: transducin beta like 1X-linked (TBL1X) Homo sapiens The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have bee

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; ICC

Species Cross-Reactivity: Human

GeneID (Human): 6907

Protein MW (KDa): 58

SWISS: O60907

Source: Mouse

Research Use Only