TBL1XR1 Monoclonal Antibody - RA12061

TBL1XR1 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA12061-50, RA12061-100

Citations, Manuals and MSDS Available upon request.

Background: transducin beta like 1 X-linked receptor 1 (TBL1XR1) Homo sapiens This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta) -like 1X-linked (TBL1X) . The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016],

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC

Species Cross-Reactivity: Human; Mouse; Rat; Bovine; Chicken; Dog; Pig; Zebrafish

GeneID (Human): 79718

SWISS: Q9BZK7

Source: Mouse

Research Use Only