TBP rabbit pAb - ES20613

TBP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20613-50, ES20613-100

Citations, Manuals and MSDS Available upon request.

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin

Alternate Name: TATA-box-binding protein (TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit)

Source: Rabbit

Applications: WB; IHC; IF

Dilution: WB: 1:500-1:2000 IHC: 1:50-1:200

Reactivity: Human; Rat; Mouse

Immunogen: Recombinant Protein of TBP

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 38kD

Human Gene ID: 6908

Human SWISS Prot NO: P20226

Subcellular Location: Nucleus

Research Use Only