Product Description

TBXAS1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-11128-60, E-AB-11128-120, E-AB-11128-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TBXAS1

Target Synonym: BDPLT14; CYP5; CYP5A1; Cytochrome P450 5A1; Cytochrome P450; family 5; subfamily A; polypeptide 1; FLJ52771; GHOSAL; Platelet cytochrome P450 subfamily V; Tbxas1; THAS; THAS; Thromboxane A synthase 1 (platelet); Thromboxane A synthase 1 (platelet; cytochrome P450; family 5; subfamily A); Thromboxane A synthase 1; Thromboxane A synthase 1 platelet cytochrome P450 subfamily V; Thromboxane-A synthase; TS; TXA synthase; TXAS; TXS

Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P24557

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.7 mg/mL

Immunogen: Recombinant protein of human TBXAS1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only