Product Description

TCAP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8422-50, BS8422-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Titin, also known as connectin, is a large protein involved in the temporal and spatial control of the assembly of the highly ordered sarcomeres (contractile units) of striated muscle . In addition to sarcomere assembly titin also functions to maintain the structural integrity of the contracting myofibrils within the muscle as well as organizing the machinery for condensation of chromosomes in dividing cells. Titin is a giant protein composed of 27, 000 amino acids and contains an autoregμlated serine kinase catalytic domain as well as a calcium/calmodμlin binding region that are involved in its activation . Activated titin phosphorylates the muscle protein telethonin, a sarcomeric protein abundant in heart and skeletal muscle, implicating titin activity in the reorganization of the cytoskeleton during myofibrillogenesis .

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF

Alternate Names: Telethonin, Titin cap protein, CAP

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human TCAP.

Dilution: WB: 1:500~1:2000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TCAP polyclonal antibody detects endogenous levels of TCAP protein.

Molecular Weight: ~ 19 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O15273

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only