Product Description

TCEA1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11677-50, MB11677-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P23193

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.MiscellaneousS-II binds to RNA-polymerase II in the absence of transcription.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 34 kDa; Observed MW: 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TCEA1 in rat spleen lysates using TCEA1 antibody., Western blot analysis of TCEA1 in EAHY, K562 lysates using TCEA1 antibody.

Alternative Name: SII; TCEA; TF2S; GTF2S; TFIIS

Immunogen: A synthetic peptide of human TCEA1

Conjugate: Unconjugated

Modification: Unmodified