Product Description

TCF19 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61732-50, BS61732-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid protein that contains one FHA domain, a proline-rich domain and one PHD-type zinc finger. Localizing to the nucleus, TCF-19 is a growth regμlated protein that is believed to function as a trans-activating factor with a role in the transcription of genes involved in the late stages of cell cycle progression (G1 to S transition or entry of cells into G2 and mitosis). TCF-19 is expressed preferentially in the G1-S phase of the cell cycle. The gene encoding TCF-19 localizes to a critical region on chromosome 6 that has been associated with psoriasis vμlgaris, a disorder of the skin that is characterized by hyperproliferation of epidermal cells. This suggests that TCF-19, via its regμlation of late cell cycle-specific genes, may play a role in the development of this disorder.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Transcription factor 19, TCF-19, Transcription factor SC1, TCF19, SC1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human TCF19.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TCF19 polyclonal antibody detects endogenous levels of TCF19 protein.

Molecular Weight: ~ 37 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y242

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only