Product Description

TCFL5 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30363-50, RA30363-100

Citations, Manuals and MSDS Available upon request.

Background: developmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids.,disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively.,function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: TCFL5; CHA; E2BP1; Transcription factor-like 5 protein; Cha transcription factor; HPV-16 E2-binding protein 1; E2BP-1

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 10732

Protein MW (KDa): 48

SWISS: Q9UL49

Source: Rabbit

Research Use Only