TCFL5 rabbit pAb - ES4545

TCFL5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4545-50, ES4545-100

Citations, Manuals and MSDS Available upon request.

Background: developmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids., disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively., function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis., similarity:Contains 1 basic helix-loop-helix (bHLH) domain., subunit:Efficient DNA binding requires dimerization with another bHLH protein., tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,

Alternate Name: TCFL5; CHA; E2BP1; Transcription factor-like 5 protein; Cha transcription factor; HPV-16 E2-binding protein 1; E2BP-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human TCFL5. AA range:311-360

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 48kD

Human Gene ID: 10732

Human SWISS Prot NO: Q9UL49

Subcellular Location: Nucleus

Research Use Only