Product Description

TCTP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91325-50, BS91325-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P13693(Human) P63028(Mouse) P63029(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IHC, FC, IP,

All Applications: WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: TCTP polyclonal antibody detects endogenous levels of TCTP protein.

Bioworld Molecular Weight: 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of TCTP on different lysates using anti-TCTP antibody at 1/1,000 dilution. Positive control:
Lane 1: Mouse placenta tissue
Lane 2: Mouse testis tissue
Lane 3: Hela
Lane 4: A431
Lane 5: MCF-7, ICC staining TCTP in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: TCTP, HRF, TPT1, FLJ27337, Fortilin, Histamine releasing factor, Histamine-releasing factor, HRF, Immunoglobulin E-dependent, p02, p23, TCTP, TCTP, tpt1, Translationally controlled tumor protein, Translationally-controlled tumor protein, Tumor protein translationally controlled 1, tumor protein, translationally-controlled 1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified