TDP 43 Monoclonal Antibody-MB11680

TDP 43 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11680-50, MB11680-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q13148

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 45 kDa; Observed MW: 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of TDP 43 in 293t using TDP 43 antibody, and DAPI., Immunohistochemistry analysis of paraffin-embedded Human brain using TDP 43 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of TDP43 in K562, C6, 3T3, Hela lysates using TDP43 antibody

Alternative Name: ALS10; TDP-43

Immunogen: A synthetic peptide of human TDP43

Conjugate: Unconjugated

Modification: Unmodified