TEL Polyclonal Antibody - BT-AP08918

TEL Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08918-20, BT-AP08918-50, BT-AP08918-100

Citations, Manuals and MSDS Available upon request.

Background: ETV6 encodes an ETS family transcription factor. The product of ETV6 contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. ETV6 is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: ETV6

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: TEL Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 53000

UniProt Accession: Human: P41212; Mouse: P97360

Synonyms: ETV6; TEL; TEL1; Transcription factor ETV6; ETS translocation variant 6; ETS-related protein Tel1; Tel

GeneID: Human: 2120

Research Use Only