Tenascin-X rabbit pAb - ES7410

Tenascin-X rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7410-50, ES7410-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: TNXB; HXBL; TNX; TNXB1; TNXB2; XB; Tenascin-X; TN-X; Hexabrachion-like protein

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human TNXB. AA range:1761-1810

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 7148

Human SWISS Prot NO: P22105

Subcellular Location: Secreted, extracellular space, extracellular matrix.

Research Use Only