Tensin-1 (phospho Tyr1326) rabbit pAb - ES1531

Tensin-1 (phospho Tyr1326) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1531-50, ES1531-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],

Alternate Name: TNS1; TNS; Tensin-1

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Tensin-1 (phospho Tyr1326)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 185kD

Human Gene ID: 7145

Human SWISS Prot NO: Q9HBL0

Subcellular Location: Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.

Research Use Only