TES Polyclonal Antibody - E-AB-67822

TES Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67822-60, E-AB-67822-120, E-AB-67822-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TES

Target Synonym: TES; TESS; TESS-2; testin

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9UGI8

Background: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TES (NP_056456.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only