TESC Polyclonal Antibody - E-AB-92902

TESC Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92902-60, E-AB-92902-120, E-AB-92902-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TESC

Target Synonym: TESC; CHP3; TSC; tescalcin

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96BS2

Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+/H(+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TESC

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 18kDa/21kDa/24kDa

Observed MW: 30kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only