TetrasPanin-8 (S129) Polyclonal Antibody-BS2467

TetrasPanin-8 (S129) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2467-50, BS2467-100

Sizes: 50µl, 100µl

Swiss-Prot: P19075

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Tetraspanin-8 (S129) polyclonal antibody detects endogenous levels of Tetraspanin-8 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Tetraspanin-8 (S129) polyclonal antibody at 1:500 dillution
Lane 1: Hct116 whole cell lysate
Lane 2: SGC7901 whole cell lysate
Lane 3: DLD whole cell lysate
Lane 4: The Kidney tissue lysate of Mouse
Lane 5: The Intestines tissue lysate of Rat
Lane 6: BV2 whole cell lysate, Immunohistochemistry (IHC) analyzes of Tetraspanin-8 (S129) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 26 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Tetraspanin-8; Tspan-8; Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029; TSPAN8; TM4SF3

Immunogen: Synthetic peptide, corresponding to amino acids 110-160 of Human Tetraspanin-8.

Conjugate: Unconjugated

Modification: Unmodified