Product Description

TFCP2L1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS74759-50, BS74759-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs. With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity. Required for normal duct development in the salivary gland and kidney (By similarity. Coordinates the development of the kidney collecting ducts intercalated (IC and principal (PC cells, which regμlate acid-base and salt-water homeostasis, respectively (By similarity. Regμlates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity. Regμlates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity. JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity. Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity. Modμlates the placental expression of CYP11A1.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: TFCP2L1, CRTR1, LBP-9, LBP9

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human TFCP2L1(NP_055368.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 58kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NZI6

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only