Product Description

TFE3 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A7936-20, A7936-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 62kDa

Observed Molecular Weight: 75kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 7030

SWISS: P19532

Alternate Names: TFEA; RCCP2; RCCX1; MRXSPF; bHLHe33; TFE3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Immunology Inflammation.

NCBI Alias: TFE3

Research Use Only