TFF1 Polyclonal Antibody-BS60275

TFF1 Polyclonal Antibody

Catalogue Numbers: BS60275-50, BS60275-100

Sizes: 50µl, 100µl

Alternative Name: Trefoil factor 1; Breast cancer estrogen-inducible protein; PNR-2; PNR2; Polypeptide P1.A; hP1.A; Protein pS2; BCEI; PS2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P04155

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: TFF1 polyclonal antibody detects endogenous levels of TFF1 protein.

Bioworld Molecular Weight: ~ 11 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TFF1 polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 cell lysate
Lane 2: Mouse kideny tissue lysate
Lane 3: Rat kidney tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human TFF1.

Conjugate: Unconjugated

Modification: Unmodified