TFPI Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A12692-20, A12692-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF) -dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 35kDa
Observed Molecular Weight: 32kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 7035
SWISS: P10646
Alternate Names: EPI; TFI; LACI; TFPI1; TFPI
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cardiovascular, Blood.
NCBI Alias: TFPI
Research Use Only