TGFβ RIII rabbit pAb - ES7381

TGFβ RIII rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7381-50, ES7381-100

Citations, Manuals and MSDS Available upon request.

Background: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010],

Alternate Name: TGFBR3; Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human TGF beta Receptor III. AA range:801-850

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 7049

Human SWISS Prot NO: Q03167

Subcellular Location: Secreted. Secreted, extracellular space. Cell membrane; Single-pass type I membrane protein. Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.

Research Use Only