Product Description

TGF β Receptor I Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16094-60, E-AB-16094-120, E-AB-16094-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TGFBR1

Target Synonym: AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin A receptor type II like kinase; 53kD; Activin A receptor type II like protein kinase of 53kD; activin A receptor type II-like kinase; 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor like kinase 5; Activin receptor-like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK-5; ALK5; LDS1A; LDS2A; MSSE; Serine/threonine protein kinase receptor R4; Serine/threonine-protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TbetaR-I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR 1; TGFBR1; TGFBR1 protein; TGFR 1; TGFR-1; TGFR1; TGFR1; Transforming growth factor beta receptor 1; Transforming growth factor beta receptor I (activin A receptor type II like kinase; 53kD); Transforming growth factor beta receptor I; transforming growth factor; beta receptor 1; transforming growth factor; beta receptor I (activin A receptor type II-like kinase; 53kD); Transforming growth factor-beta receptor type I

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P36897

Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human TGFBR1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:100-1:300

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only