Product Description

TGF beta 1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91338-50, BS91338-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P01137

Host: Rabbit

Reactivity: Mouse, Rat

Applications: IF/ICC

All Applications: IF/ICC,1:50 - 1:200

Background: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Polyclonal Antibodies

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of NIH/3T3 cells using TGF beta 1 Rabbit pAb at dilution of 1:100. Blue: DAPI for nuclear staining.

Alternative Name: TGFB1; CED; DPD1; LAP; TGFB; TGFbeta; TGF-β

Immunogen: Recombinant fusion protein of human TGF beta 1(NP_000651.3).

Conjugate: Unconjugated

Modification: Unmodified