TGF beta1 Monoclonal Antibody - BT-MCA3253

TGF beta1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3253-50, BT-MCA3253-100

Citations, Manuals and MSDS Available upon request.

Background: TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.

Research Areas: Others

Target Protein: TGF beta1

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4F9C10

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: TGF beta1

Immunogen: Purified recombinant fragment of TGF beta1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P01137

Synonyms: CED, DPD1, TGFB, TGFbeta, TGFB1

GeneID: 7040

Research Use Only