Product Description

TGFBR1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40428-60, E-AB-40428-120, E-AB-40428-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: TGFBR1

Target Synonym: AAT5; Activin A receptor type II like kinase; Activin receptor like kinase 5; ACVRLK4; ALK5; LDS1A; LDS2A; MSSE; SKR4; TGF beta receptor type 1; TGFBR1 protein; TGFR1; Transforming growth factor beta receptor 1

Research Areas: Cardiovascular, Signal Transduction, Stem Cells, Cancer, Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P80204

Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant Rat TGF-beta receptor type-1 protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:500-1:2000 IHC 1:100-1:300

Calculated MW: 56 kDa

Observed MW: 56 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only