Product Description

THAP11 Monoclonal Antibody

Catalogue Numbers: MB67174-50, MB67174-100

Sizes: 50µl, 100µl

Product: Mouse IgM. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q96EK4

Host: Mouse

Reactivity: Human, Mouse

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Thanatos-associated protein (Thap) proteins are a family of cellular factors that are characterized by an evolutionarily conserved protein motif similar to the DNA-binding domain of Drosophila P element transposase. There are 12 known human Thap proteins that all act as site-specific DNA-binding factors involved in transcriptional regulation, cell proliferation, chromatin modification, and apoptosis. Human Thap11 has been shown to suppress cell growth through transcriptional suppression of c-Myc. The mouse homolog of Thap11, Ronin, has been identified as an essential factor underlying embryogenesis in mouse embryonic stem cells.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of THAP11 protein.

Extra Notes: Western blot analysis of THAP11 expression in HepG2 (A) whole cell lysates.

Bioworld Molecular Weight: ~ 33 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: THAP domain-containing protein 11

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human THAP11. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified