Product Description

THG1L Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53131-60, E-AB-53131-120, E-AB-53131-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: THG1L

Target Synonym: ICF45; Interphase cytoplasmic foci protein 45; Probable tRNA(His) guanylyltransferase; THG1; THG1L; tRNA histidine guanylyltransferase 1 like (S. cerevisiae); tRNA-histidine guanylyltransferase

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NWX6

Background: The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.9 mg/mL

Immunogen: Fusion protein of human THG1L

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only