Thioredoxin Reductase 1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11739-50, MB11739-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q16881
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB, IHC-F, IHC-P, ICC/IF, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Background: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 71 kDa; Observed MW: 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of TXNRD1 in 3T3 lysates using Thioredoxin Reductase 1 antibody., Western blot analysis of TXNRD1 in K562, Hela lysates using TXNRD1 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using TXNRD1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of TXNRD1 in Hela using TXNRD1 antibody, and DAPI.
Alternative Name: TR; TR1; TXNR; TRXR1; GRIM-12
Immunogen: Recombinant protein of human TXNRD1
Conjugate: Unconjugated
Modification: Unmodified