Thrombospondin 1 rabbit pAb - ES12729

Thrombospondin 1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES12729-50, ES12729-100

Citations, Manuals and MSDS Available upon request.

Background: thrombospondin 1 (THBS1) Homo sapiens The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008],

Alternate Name: Thrombospondin-1

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human Thrombospondin 1

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 130kD

Human Gene ID: 7057

Human SWISS Prot NO: P07996

Subcellular Location: Secreted. Cell surface. Secreted, extracellular space, extracellular matrix. Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted by thrombin-activated platelets and binds to the cell surface in the presence of extracellular Ca (2+) (PubMed:6777381). Incorporated into the extracellular matrix of fibroblasts (PubMed:6341993). Also detected in the endoplasmic reticulum and sarcoplasmic reticulum where it plays a role in the ER stress response (By similarity).

Research Use Only