Product Description

thymidine phosphorylase Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65869-50, BS65869-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC-P

Alternate Names: ECGF 1, PDEGF, ECGF1, Endothelial cell growth factor 1, Endothelial cell growth factor 1 platelet derived, Gliostatin, hPD ECGF, MNGIE, PD ECGF, PDECGF, PDEGF, Platelet derived endothelial growth factor, TdRPase, TP, TYMP, Thymidine Phosphorylase, TYPH_HUMAN, TdRPase.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase:121-220/482

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: thymidine phosphorylase Polyclonal Antibody detects endogenous levels of thymidine phosphorylase protein.

Molecular Weight: ~50kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -42°C long term. Avoid freeze-thaw cycles.

SwissProt: P19971

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only